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Age-related resistance to 987P fimbria-mediated colonization correlates with specific glycolipid receptors in intestinal mucus in swine
1994
Infection and Immunity
Strains of enterotoxigenic Escherichia col that produce 987P fimbriae (987P+ strains) colonize the small intestines and cause diarrhea in neonatal (<6-day-old) pigs but not in weaned pigs. However, 987P+ E. coli strains adhere in vitro to intestinal epithelial cells from pigs of both ages. Two intestinal components, designated 987R and 987M, bind 987P fimbriae (987P) on Western blots (immunoblots). We examined brush borders (BB) and intestinal washes (IW) from pigs to determine if they contain
doi:10.1128/iai.62.11.4789-4794.1994
fatcat:76joqupaxfc6zkp6lztjjaeiiu