Whole Cell Recordings of Lumbar Motoneurons During Locomotor-Like Activity in the In Vitro Neonatal Rat Spinal Cord

S. Hochman, B. J. Schmidt
1998 Journal of Neurophysiology  
Hochman, S. and B. J. Schmidt. Whole cell recordings of lumbar central pattern generator (CPG) for locomotion (for review, motoneurons during locomotor-like activity in the in vitro neonatal see Gossard and Hultborn 1991). Progress in this area has rat spinal cord. J. Neurophysiol. 79: 743-752, 1998. Whole cell been hampered, in part, by the inherent difficulties of trying current-and voltage-clamp recordings were obtained from lumbar to identify the essential interneuronal components of the
more » ... oneurons in the isolated neonatal rat spinal cord to characterize CPG using electrophysiological criteria. the behavior of motoneurons during neurochemically induced loco-One approach to delineating CPG organization, as used motor-like activity. Bath application of serotonin (10-100 mM) in 743 0022-3077/98 $5.00
doi:10.1152/jn.1998.79.2.743 pmid:9463437 fatcat:5jdwij6ke5b4zgsp5fgm5fethi