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The objective: identification of the main predictors of progression of disability in patients with multiple sclerosis (MS ) , depending on the clinical and neuroimaging factors. Patients and methods. The data presented was collected during a ten year observation of 180 patients with relapsing remitting multiple sclerosis (RRRS) from the first clinical signs of the disease (CIS). Age surveyed ranged from 18 to 42 years old with a mean of 31,5 ± 1,18 years . We determined clinical anddoi:10.30841/2307-5112.2(64).2016.102485 doaj:d2448b353f994e559efe60b5dce7d9eb fatcat:ahh3zzwltreevdqcvobferdooi