Pemphigus Vegetans of Neumann Type on Lip: A Case Report

Anil P Gosavi, Ravindranath Brahmadeo Chavan, Jheel Shriniwas Ambike, Nitika S Deshmukh
2021 Journal of Skin and Stem Cell  
: Pemphigus is a chronic autoimmune vesiculobullous disease caused by autoantibodies directed against desmogleins (Dsgs). Pemphigus vegetans is a rare variant of pemphigus vulgaris, characterized by vegetative plaques, primarily occurring in flexures. It is a less common disease and involves the skin and mucosa due to disintegration of cellular adherence (acantholysis), resulting in intradermal split. We report this case of pemphigus vegetans of Neumann type for its rare presentation. We report
more » ... entation. We report a case of pemphigus vegetans, involving lips in a middle-aged female and sparing flexural areas. This patient was diagnosed on the basis of histopathology and treated successfully with intralesional steroids, resulting in the resolution of her plaques.
doi:10.5812/jssc.108089 fatcat:egzlpx6jbngb7imb4mcj6nqjhu