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Huntington's Disease Mouse Models Online: High-Resolution MRI Images with Stereotaxic Templates for Computational Neuroanatomy
2012
PLoS ONE
Magnetic resonance imaging (MRI) has proved to be an ideal modality for non-destructive and highly detailed assessment of structural morphology in biological tissues. Here we used MRI to make a dataset of ex vivo brains from two different rodent models of Huntington's disease (HD), the R6/2 line and the YAC 128 mouse. We are making the whole dataset (399 transgenic HD and wildtype (WT) brains, from mice aged 9-80 weeks) publicly available. These data will be useful, not only to investigators
doi:10.1371/journal.pone.0053361
pmid:23300918
pmcid:PMC3534048
fatcat:hb6c3cw66bggbpy6miqwfjhipa