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Comparative Analysis of RNA Families Reveals Distinct Repertoires for Each Domain of Life
2012
PLoS Computational Biology
The RNA world hypothesis, that RNA genomes and catalysts preceded DNA genomes and genetically-encoded protein catalysts, has been central to models for the early evolution of life on Earth. A key part of such models is continuity between the earliest stages in the evolution of life and the RNA repertoires of extant lineages. Some assessments seem consistent with a diverse RNA world, yet direct continuity between modern RNAs and an RNA world has not been demonstrated for the majority of RNA
doi:10.1371/journal.pcbi.1002752
pmid:23133357
pmcid:PMC3486863
fatcat:vcxky4j3nzfsnl3ymu7n4xudoq