Context: vitiligo with a unique location in the penis is a rare entity. Presentation of the case: A 34-year-old man who presented himself in our training, he complained of a whitish plaque on his penis. The physical examination showed an achromic macule on the level of the penis, with a catch of contrast in light of Wood. A skin biopsy of the dorsal surface of the penis showed a total absence of melanocytes and melanin granules in the basal layer.