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Induction of dendritic cell-like phenotype in macrophages during foam cell formation
2007
Physiological Genomics
Induction of dendritic cell-like phenotype in macrophages during foam cell formation. Foam cell formation from monocyte-derived macrophages is a hallmark of atherosclerotic lesions. Aspects of this process can be recapitulated in vitro by exposing M-CSF-induced or platelet factor 4 (CXCL4)induced macrophages to oxidized (ox) or minimally modified (mm) low density lipoprotein (LDL). We measured gene expression in peripheral blood mononuclear cells, monocytes, and macrophages treated with CXCL1
doi:10.1152/physiolgenomics.00051.2006
pmid:17244792
fatcat:6sfvhwk4p5d3tdbsqawq4h77ci