This study aimed to investigate the pattern of gastric cells count in peptic ulcer patients. 200 patients with peptic ulcer disease were included in this study, 160 of them have Du and 40 of them have GU. Eighty normal subjects were considered as control group .We had performed gastric antral, and gastric body mucosal biopsy for all these patients with peptic ulcer and including the control group in order to study the histopathological pattern of gastric mucosal cells. The results, of this

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... showed that the parietal cells count significantly (P< 0.01) higher in duodenal ulcer patients than normal control group and also significantly lower in gastric ulcer patients than control group. There was no significant difference in parietal cells counts in peptic ulcer patients wether infected with H-pylori or non infected with H.pylori. Also the chief cells count was significantly (P<0. 05) higher in duodenal ulcer patients than control and was significantly Lower in gastric ulcer patients than control. H-pylori infection has no effect on chief cells count in Du and Gu patients than control group. mucous cells count was significantly (p0.05) in D-cells and G-cells count between duodenal ulcer patients and control group, but there was a significant decrease in D-cells and G-cells count in gastric ulcer patients than control. H.pylori infection has no effect on D-cells and G-cells count in peptic ulcer patients. ‫اﻟﺨﻼﺻﺔ‬ ‫ﺍﻟﻬﻀﻤﻴﺔ‬ ‫ﺍﻟﻘﺭﺤﺔ‬ ‫ﻟﻤﺭﻀﻰ‬ ‫ﺍﻟﻤﻌﺩﻴﺔ‬ ‫ﺍﻟﺨﻼﻴﺎ‬ ‫ﺒﺄﻋﺩﺍﺩ‬ ‫ﺍﻟﺘﻐﻴﺭ‬ ‫ﻟﻤﻌﺭﻓﺔ‬ ‫ﺍﻟﺩﺭﺍﺴﺔ‬ ‫ﻫﺫﻩ‬ ‫ﻫﺩﻓﺕ‬. ‫ﺍﻟﺩﺭﺍﺴﺔ‬ ‫ﻫﺫﻩ‬ ‫ﺘﻀﻤﻨﺕ‬ 200 ‫ﻤﺭﻀـﻰ‬ ‫ﻤﻥ‬ ‫ﻤﺭﻴﺽ‬ ، ‫ﺍﻟﻬﻀﻤﻴﺔ‬ ‫ﺍﻟﻘﺭﺤﺔ‬ 160 ‫ﻭ‬ ‫ﻋﺸﺭ‬ ‫ﺃﻻﺜﻨﻲ‬ ‫ﺒﻘﺭﺤﺔ‬ ‫ﻤﺭﻴﺽ‬ ‫ﻤﻨﻬﻡ‬ 40 ‫ﺍﻟﺩﺭﺍﺴﺔ‬ ‫ﻭﺸﻤﻠﺕ‬ ‫ﺍﻟﻤﻌﺩﺓ‬ ‫ﺒﻘﺭﺤﺔ‬ ‫ﻤﺼﺎﺏ‬ ‫ﻤﻨﻬﻡ‬ 80 ‫ﺍﻷﺼﺤﺎﺀ‬ ‫ﺍﻟﻨﺎﺱ‬ ‫ﻤﻥ‬ ‫ﻜﻤﺠ‬ ‫ﺍﺩﺨﻠﻭﺍ‬ ‫ﺴﻴﻁﺭﺓ‬ ‫ﻤﻭﻋﺔ‬. ‫ﺃﺨﺫﺕ‬ ‫ﺨﺯﻋﺔ‬ ‫ﻤﻥ‬ ‫ﻏﺎﺭ‬ ‫ﺍﻟﻨـﺴﺠﻴﺔ‬ ‫ﺍﻟﺩﺭﺍﺴﺔ‬ ‫ﻟﻐﺭﺽ‬ ‫ﻭﺍﻷﺼﺤﺎﺀ‬ ‫ﺍﻟﻬﻀﻤﻴﺔ‬ ‫ﺍﻟﻘﺭﺤﺔ‬ ‫ﻤﺭﻀﻰ‬ ‫ﻤﻥ‬ ‫ﻟﻜل‬ ‫ﺍﻟﻤﻌﺩﺓ‬ ‫ﻭﺠﺴﻡ‬ ‫ﺍﻟﻤﻌﺩﺓ‬ ‫ﻓﻲ‬ ‫ﺍﻟﻤﺨﺘﻠﻔﺔ‬ ‫ﻟﻠﺨﻼﻴﺎ‬. ‫ﻤﻌﻨﻭﻴﺔ‬ ‫ﺯﻴﺎﺩﺓ‬ ‫ﻭﺠﻭﺩ‬ ‫ﺃﻭﻀﺤﺕ‬ ‫ﺍﻟﺩﺭﺍﺴﺔ‬ ‫ﻫﺫﻩ‬ ‫ﻨﺘﺎﺌﺞ‬) (P< 0.01 ‫ﺍﻟﺠﺩﺍﺭﻴﺔ‬ ‫ﺍﻟﺨﻼﻴﺎ‬ ‫ﺇﻋﺩﺍﺩ‬ ‫ﻓﻲ‬ ‫ﻤﻘﺎﺭﻨـﺔ‬ ‫ﻋـﺸﺭﻱ‬ ‫ﺍﻻﺜﻨﻲ‬ ‫ﻗﺭﺤﺔ‬ ‫ﻤﺭﻀﻰ‬ ‫ﻓﻲ‬ ‫ﺍﻟﺴﻴﻁﺭﺓ‬ ‫ﺒﻤﺠﻤﻭﻋﺔ‬ ‫ﺍﻟـﺴﻴﻁﺭﺓ‬ ‫ﺒﻤﺠﻤﻭﻋـﺔ‬ ‫ﻤﻘﺎﺭﻨـﺔ‬ ‫ﺍﻟﻤﻌـﺩﺓ‬ ‫ﻗﺭﺤﺔ‬ ‫ﻤﺭﻀﻰ‬ ‫ﻓﻲ‬ ‫ﺇﻋﺩﺍﺩﻫﺎ‬ ‫ﻓﻲ‬ ‫ﻤﻌﻨﻭﻱ‬ ‫ﺍﻨﺨﻔﺎﺽ‬ ‫ﻭﻭﺠﻭﺩ‬. ‫ﺘـﺄﺜﻴﺭ‬ ‫ﻴﻭﺠـﺩ‬ ‫ﻻ‬ ‫ﻤﻌﻨﻭﻱ‬) P>0.05 (‫ﺍﻟﺠﺩﺍﺭﻴﺔ‬ ‫ﺍﻟﺨﻼﻴﺎ‬ ‫ﺍﻋﺩﺍﺩ‬ ‫ﻋﻠﻰ‬ ‫ﺒﺎﻴﻠﻭﺭﻱ‬ ‫ﺍﻟﻬﻠﻜﻭﺒﻜﺘﺭﻴﺎ‬ ‫ﻟﺒﻜﺘﺭﻴﺎ‬. ‫ﻤﻌﻨﻭﻱ‬ ‫ﺍﺭﺘﻔﺎﻉ‬ ‫ﻭﺠﺩ‬ ‫ﻜﺫﻟﻙ‬) (P< 0.01 ‫ﺍﻋـﺩﺍﺩ‬ ‫ﻓـﻲ‬ ‫ﺒ‬ ‫ﻤﻘﺎﺭﻨﺔ‬ ‫ﻋﺸﺭ‬ ‫ﺍﻻﺜﻨﻲ‬ ‫ﻗﺭﺤﺔ‬ ‫ﻤﺭﻀﻰ‬ ‫ﻓﻲ‬ ‫ﺍﻟﺭﺌﻴﺴﻴﺔ‬ ‫ﺍﻟﺨﻼﻴﺎ‬ ‫ﻓﻲ‬ ‫ﻤﻌﻨﻭﻱ‬ ‫ﻭﺍﻨﺨﻔﺎﺽ‬ ‫ﺍﻟﺴﻴﻁﺭﺓ‬ ‫ﻤﺠﻤﻭﻋﺔ‬ ‫ﻤﻘﺎﺭﻨﺔ‬ ‫ﺍﻟﻤﻌﺩﺓ‬ ‫ﻗﺭﺤﺔ‬ ‫ﻤﺭﻀﻰ‬ ‫ﻓﻲ‬ ‫ﺃﻋﺩﺍﺩﻫﺎ‬ ‫ﺍﻟﻬﻠﻜﻭﺒﻜﺘﺭ‬ ‫ﻟﺒﻜﺘﺭﻴﺎ‬ ‫ﻴﻜﻥ‬ ‫ﻭﻟﻡ‬ ‫ﺒﺎﻟﺴﻴﻁﺭﺓ‬ ‫ﺘﺄﺜﻴﺭﺍ‬ ‫ﺒﺎﻴﻠﻭﺭﻱ‬ ‫ﹰ‬ ‫ﻤﻌﻨﻭﻴﺎ‬) (P > 0.05 ‫ﺍﻟﺭﺌﻴﺴﻴﺔ‬ ‫ﺍﻟﺨﻼﻴﺎ‬ ‫ﺃﻋﺩﺍﺩ‬ ‫ﻋﻠﻰ‬. ‫ﻤﻌﻨﻭﻱ‬ ‫ﺍﻨﺨﻔﺎﺽ‬ ‫ﻭﺠﻭﺩ‬