Effect of AEDs on Learning and Behavior

J Gordon Millichap
1998 Pediatric Neurology Briefs  
The inappropriate use of carbamazepine (CBZ) in 8 children, and vigabatrin (VGB) in 2, among 18 consecutive referrals of children with resistant typical absence seizures, is reported from St Thomas' and Guy's Hospitals, London, UK. Frequency of absences had increased in 4 of the children who received CBZ and 2 of these developed myoclonic jerks in addition, which resolved after CBZ withdrawal. Typical absence epilepsy was confirmed by EEG, video-EEG, or both. Subsequent control of seizures was
more » ... btained with valproate, lamotrigine, or ethosuximide. (Parker APJ, Agathonikou A, Robinson RO, Panayiotopoulos CP. Inappropriate use of carbamazepine and vigabatrin in typical absence seizures.
doi:10.15844/pedneurbriefs-12-10-6 fatcat:oldvn45cpbgnxkl6zxd4gf2uoe