Epidemiology of Non-Alcoholic Fatty Liver Disease

Stefano Bellentani, Federica Scaglioni, Mariano Marino, Giorgio Bedogni
2010 Digestive Diseases  
general population. The most important risk factors for NAFLD are male gender, age, obesity, insulin resistance and the cardiometabolic alterations that define the metabolic syndrome. The prevalence of NAFLD is 80-90% in obese adults, 30-50% in patients with diabetes and up to 90% in patients with hyperlipidemia. The prevalence of NAFLD among children is 3-10%, rising up to 40-70% among obese children. Moreover, pediatric NAFLD increased from about 3% a decade ago to 5% today, with a
more » ... , with a male-to-female ratio of 2: 1. The incidence and natural history of NAFLD are still not well defined, but it is recognized that the majority of individuals with NAFLD do not develop NASH. The incidence of NAFLD is probably increasing in Western countries, strictly linked to lifestyle habits.
doi:10.1159/000282080 pmid:20460905 fatcat:dwtvacp7vnfa5f6lkyzh3pzeea