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F1000 - Post-publication peer review of the biomedical literature
Pathogenic enterobacteria face various oxygen (O 2 ) levels during intestinal colonization from the O 2 -deprived lumen to oxygenated tissues. Using Shigella flexneri as a model, we had previously demonstrated that epithelium invasion is promoted by O 2 in a Type III secretion system (T3SS)dependent manner 1 . However, subsequent pathogen adaptation to tissue oxygenation modulation remained unknown. Assessing single-cell distribution, together with tissue oxygenation, we demonstrate here thatdoi:10.3410/f.736415614.793566151 fatcat:hq42tzajl5akhnks2ekrhb6feu