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Ovarian Cancer - From Pathogenesis to Treatment
Precision medicine in cancer is the idea that the recognition and targeting of key genetic drivers of a patient's tumor can permit more effective and less toxic outcomes. Point mutations that alter protein function have been primary targets. Yet in ovarian cancer, unique genetic mutations have been identified only in adult granulosa cell tumors, with a number of other point mutations present in mucinous, clear cell and endometrioid carcinoma subtypes. By contrast, the serous subtype of ovariandoi:10.5772/intechopen.72695 fatcat:voti2ifovfdqfpxdftfqf7cq64