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Immunological Demyelination Triggers Macrophage/Microglial Cells Activation without Inducing Astrogliosis
2013
Clinical and Developmental Immunology
The glial scar formed by reactive astrocytes and axon growth inhibitors associated with myelin play important roles in the failure of axonal regeneration following central nervous system (CNS) injury. Our laboratory has previously demonstrated that immunological demyelination of the CNS facilitates regeneration of severed axons following spinal cord injury. In the present study, we evaluate whether immunological demyelination is accompanied with astrogliosis. We compared the astrogliosis and
doi:10.1155/2013/812456
pmid:24319469
pmcid:PMC3844255
fatcat:5wlc3akwenftvgkktptqcjrt4u