A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2018; you can also visit the original URL.
The file type is application/pdf.
The Clinical Pharmacology of Lidocaine as an Antiarrhythymic Drug
1974
Circulation
Preserved Fulltext
This article reviews current knowledge about lidocaine, with reference to its chemistry, metabolism, electrophysiology, hemodynamic effects, antiarrhythmic uses, pharmacokinetics, and side effects. The critical importance of blood levels and their relation to lidocaine's antiarrhythmic and toxic effects is noted, with special emphasis given to patients with compromised clearance due to heart failure. On the basis of this information, we present our current approach to the clinical use of
doi:10.1161/01.cir.50.6.1217
pmid:4609637
fatcat:4bjcizgvwnhezatide6fai2oi4