Chitosan-Curcumin Coating Characterization on Cobalt-Chrome Surface by 100 kHz Ultrasonic Spray Method

Katiko Imamul Muttaqin
2021 Journal of Materials Processing and Characterization  
Curcumin possesses anticoagulant, anti-proliferative, and anti-inflammatory properties and is applicable to prevent in-stent restenosis. This research investigated curcumin coating with biodegradable chitosan polymer as a drug carrier universally made on Co-Cr L605 surface by the ultrasonic spray method. Three curcumin doses were implemented: low dose (150 μg of curcumin per sample), medium dose (300 μg of curcumin per sample), and high dose (480 μg of curcumin per sample). The metal surface
more » ... phologies before and after coating were examined by using a stylus profilometer and a scanning electron microscope (SEM). The result showed that coating films were formed fine and uniform with an average roughness level below 0.2 μm. The coating film structure characterization by Fourier-transform infrared (FTIR) spectroscopy showed that curcumin absorption spectra still occurred in the chitosan-curcumin coating, although chitosan strong absorption spectra were dominant.
doi:10.22146/jmpc.68281 fatcat:iopa56wqxrh3xpovbg54brf2de