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New Directions in the Genomics of Allogeneic Hematopoietic Stem Cell Transplantation
2007
Biology of Blood and Marrow Transplantation
Despite optimal supportive care and high-resolution HLA matching, complications such as GVHD and infection remain major barriers to the success of allogeneic HCT (allo-HCT). This has led to growing interest in the non-HLA genetic determinants of complications after allo-HCT. Most studies have examined genetic predictors of GVHD, relapse, and mortality and have focused on 3 main areas: minor histocompatibility antigen (miHAs), inflammatory mediators of GVHD, and more recently NK cell-mediated
doi:10.1016/j.bbmt.2006.10.018
pmid:17241919
fatcat:vmeg6c2qdvawjcowsafmoeoouq