Preparation of (177Lu-DOTA)n-PAMAM-[Nimotuzumab-F(ab')2] as a Therapeutic Radioimmunoconjugate for EGFR Overexpressed Cancers Treatment

Titis Sekar Humani, Sutari Sutari, Triningsih Triningsih, Martalena Ramli, Rien Ritawidya, Ratna Dini Haryuni
2017 Journal of Mathematical and Fundamental Sciences  
Intact monoclonal antibodies with a high molecular weight tend to have a poor pharmacokinetic profile and tumor penetration, and potential for eliciting host antibody responses.
doi:10.5614/j.math.fund.sci.2017.49.3.4 fatcat:6z3owpd22nbrlfe6bbak4jysxq