The total synthesis and functional evaluation of fourteen stereoisomers of yaku'amide B. The importance of stereochemistry for hydrophobicity and cytotoxicity

Hiroyuki Mutoh, Yusuke Sesoko, Takefumi Kuranaga, Hiroaki Itoh, Masayuki Inoue
2016 Organic and biomolecular chemistry  
Yaku'amide B is a highly unsaturated linear tridecapeptide and an extremely potent cytotoxin.
doi:10.1039/c6ob00640j pmid:27102875 fatcat:lycdqj6lbbd3tefcka2txbco7i