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Gene recognition in eukaryotic DNA by comparison of genomic sequences
2001
Bioinformatics
Motivation: Sequencing of complete eukaryotic genomes and large syntenic fragments of genomes makes it possible to apply genomic comparison for gene recognition. Results: This paper describes a spliced alignment algorithm that aligns candidate exon chains of two homologous genomic sequence fragments from different species. The algorithm is implemented in Pro-Gen software. Unlike other algorithms, Pro-Gen does not assume conservation of the exon-intron structure. Amino acid sequences obtained by
doi:10.1093/bioinformatics/17.11.1011
pmid:11724729
fatcat:kvrap5zd2jd4bd7p3ywhcdqn7y