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Leukotrienes biosynthesis in coronary artery disease - results of Leukotrienes and Thromboxane In Myocardial Infarction (LTIMI) study
Polish Archives of Internal Medicine
specific enzymes and proteins, including 5 -LO, 5-LO -activating protein (FLAP), LTC 4 synthase, or LTA 4 hydrolase. 3 The main products of the LT cascade are LTC 4 , LTD 4 , and LTE 4 due to the presence of cysteine, collectively named cysteinyl leukotrienes (CysLTs), whereas LTB 4 is a potent chemoattractant of neutrophils. The final metabolite of CysLTs is LTE 4 , excreted in urine in an unchanged form or N -acetyl -LTE 4 . 1doi:10.20452/pamw.4140 pmid:29112183 fatcat:ouxi7p5h65g4rhfs4noc6c3qsa