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Fluticasone propionate -the first carbothioate corticosteroid -has been classified as a potent anti-inflammatory drug for dermatological use. It is available as 0.05% cream and 0.005% ointment formulations for the acute and maintenance treatment of patients with dermatological disorders such as atopic dermatitis, psoriasis and vitiligo. This glucocorticoid is characterized by high lipophilicity, high glucocorticoid receptor binding and activation, and a rapid metabolic turnover in skin.doi:10.1159/000081680 pmid:15608497 fatcat:l6nqezpwgzhatgty3gl2tun2iq