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Differences In The Volume Of Stress Platelets And Vincristine Stimulated Platelets
1981
Thrombosis and Haemostasis
The mechanisms by which thrombocytoses are produced are not understood. This study examines the size of platelets in thrombocytoses produced by two different stimuli.Rats were given Vincristine (0.1 mg/kg intravenously) which produced an increase in platelet count from 1.0 to 1.5 × 109/ml on day 5 without a preceding thrombocytopenia. The volume of platelets from an aliquot of the whole platelet population was measured daily using a Coulter ZF counter coupled to a 2000 channel multichannel
doi:10.1055/s-0038-1653250
fatcat:xcvsk23e6fgszect3snwmm4zou