EVALUATION OF ACETONE EXTRACT OF THREE INDIAN MEDICINAL PLANTS FOR SCHIZONTICIDAL PROPERTIES IN PLASMODIUM FALCIPARUM

Bharat Gami
2011 International Journal Of Pharmacy&Technology IJPT   unpublished
Increased resistance against Plasmodium falciparum in the present drugs is an impetus for dynamic study filed for new antimalarial agent from plants & chemically synthesized molecule. In present attempt, acetone extract of Alstonia scholaris, Moringa oleifera, and Tinospora cordifolia, was tested for schizonticidal activity of Plasmodium falciparum. The 50 % inhibitory concentration (IC 50) value range from 0.08 µM to 0.26µM. Components of acetone fraction were separated by high performance
more » ... igh performance thin layer chromatography (HPTLC) and scanned at 366 nm. All plants showed strong schizonticidal activity. All the three plant extracts by further purification could be use as an effective, alternative source of herbal anti-malarial drugs.
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