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of Medical Sciences and Health Services Iranian Journal of Pharmaceutical Research
Quinoxalines display diverse and interesting pharmacological activities as antibacterial, antiviral, antiparasitic and anticancer agents. Particularly, their 1ˏ4-diN oxide derivatives have proved to be cytotoxic agents that are active under hypoxic conditions as that of solid tumours. A new series of quinoxaline 1ˏ4-diN oxide substitutes at 7-position with esters group were synthetized and characterized by infrared (IR), proton nuclear magnetic resonance (1 H-NMR), spectroscopy, and elementalfatcat:332euphrsrg4zb6cmkmn34o3km