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Reprogramming and redifferentiation of mucosal-associated invariant T cells reveals tumor inhibitory activity
[article]
2021
bioRxiv
pre-print
Mucosal-associated invariant T (MAIT) cells belong to a family of innate-like T cells that bridge innate and adaptive immunities. Although MAIT cells have been implicated in tumor immunity, it currently remains unclear whether they function as tumor promoting or inhibitory cells. Therefore, we herein used induced pluripotent cell (iPSC) technology to investigate this issue. Murine MAIT cells were reprogrammed into iPSCs and redifferentiated towards MAIT-like cells (m-reMAIT cells). m-reMAIT
doi:10.1101/2021.06.21.449226
fatcat:wzeureymvbd57bqdpsnxlbljja