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ESCRT-III acts in scissioning new peroxisomes from the ER
[article]
2017
bioRxiv
pre-print
Dynamic control of peroxisome proliferation is integral to the peroxisome's many functions. A breakdown in the ability of cells to form peroxisomes is linked to many human health issues, including defense against infectious agents, cancer, aging, heart disease, obesity and diabetes, and forms the basis of a spectrum of peroxisomal genetic disorders that cause severe neuropathologies. The ER serves as a source for preperoxisomal vesicles (PPVs) that mature into peroxisomes during de novo
doi:10.1101/147603
fatcat:3tr6sprrh5bopnzr6v2qy5kzka