The antitoxoplasmic activity of Spiramycin and Myrrh were evaluated in murine models of intraperitoneal infection using the RH strain of Toxoplasma gondii. In mice infected with 2x10 2 tachyzoites / ml, treatment with those drugs at 100 and 200 mg/kg/day had a good effect. Administration of tested drugs intraperitoneally reduced the mean number of tachyzoites present in the peritoneal fluid of experimented mice 4 days after infection, with the treatment of 100 and 200 mg/kg/day of Myrrh the

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... entage of growth inhibitions were 96.6%, 100 % respectively, as that of the reference drug, Spiramycin, (% growth inhibitions were 96.6%, 75.9% correspondingly) compared by the control infected untreated mice.