Security Provisioning and Compression of Diverse Genomic Data based on Advanced Encryption Standard (AES) Algorithm

Raveendra Gudodagi, R. Venkata Siva Reddy
2021 International Journal of Biology and Biomedical Engineering  
Compression of genomic data has gained enormous momentum in recent years because of advances in technology, exponentially growing health concerns, and government funding for research. Such advances have driven us to personalize public health and medical care. These pose a considerable challenge for ubiquitous computing in data storage. One of the main issues faced by genomic laboratories is the 'cost of storage' due to the large data file of the human genome (ranging from 30 GB to 200 GB). Data
more » ... preservation is a set of actions meant to protect data from unauthorized access or changes. There are several methods used to protect data, and encryption is one of them. Protecting genomic data is a critical concern in genomics as it includes personal data. We suggest a secure encryption and decryption technique for diverse genomic data (FASTA / FASTQ format) in this article. Since we know the sequenced data is massive in bulk, the raw sequenced file is broken into sections and compressed. The Advanced Encryption Standard (AES) algorithm is used for encryption, and the Galois / Counter Mode (GCM) algorithm, is used to decode the encrypted data. This approach reduces the amount of storage space used for the data disc while preserving the data. This condition necessitates the use of a modern data compression strategy. That not only reduces storage but also improves process efficiency by using a k-th order Markov chain. In this regard, no efforts have been made to address this problem separately, from both the hardware and software realms. In this analysis, we support the need for a tailor-made hardware and software ecosystem that will take full advantage of the current stand-alone solutions. The paper discusses sequenced DNA, which may take the form of raw data obtained from sequencing. Inappropriate use of genomic data presents unique risks because it can be used to classify any individual; thus, the study focuses on the security provisioning and compression of diverse genomic data using the Advanced Encryption Standard (AES) Algorithm.
doi:10.46300/91011.2021.15.14 fatcat:qwaxau5ia5bsnns53unacgc7wq