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The most realistic information about the transparent sample such as a live cell can be obtained only using bright-field light microscopy. At high-intensity pulsing LED illumination, we captured a primary 12-bit-per-channel (bpc) response from an observed sample using a bright-field wide-field microscope equipped with a high-resolution (4872x3248) image sensor. In order to suppress data distortions originating from the light interactions with undesirable elements in the optical path, poor sensordoi:10.5281/zenodo.4843453 fatcat:ln6bte7fujc3vkedp7tasgubge