The involvement of prolactin is well established in mammary carcinoma in rodents.However the exact role of hormones such as oestrogen, prolactin and progesterone in human breast cancer still remains elusive.The present study was undertaken to compare the preoperative and postoperative serum prolactin levels in patients of carcinoma breast coming to the department of Surgery, Guru Nanak Dev Hospital attached to Govt. Medical College, Amritsar.. Serum prolactin levels showed a statistically

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... icant elevation in premenopausal as well as in postmenopausal patients of carcinoma breast as compared to control group. The prolactin levels were raised two days after and one month after surgery upon breast. The elevation was more marked in premenopausal patients as compared to postmenopausal patients of carcinoma breast.