COMPARISON BETWEEN CONVENTIONAL DCR AND DCR AUGMENTED WITH MITOMYCIN-C
English

Waseem Raja, Mohd. Ayaz Bhat, Mahrukh Mahrukh
2019 Journal of Evidence Based Medicine and Healthcare  
BACKGROUND Dacryocystorhinostomy (DCR) is done for management of epiphora due to nasolacrimal duct obstruction. Common causes of DCR failure are fibrous tissue growth, scarring and granulation tissue formation which obstructs the new drainage channel formed after conventional DCR surgery. Mitomycin-C is an anti-proliferative agent and may enhance the result of DCR by inhibiting fibrous tissue proliferation. MATERIALS AND METHODS A prospective randomized comparative study of one-year duration
more » ... done in the Department of Ophthalmology, District Hospital, Pulwama, Kashmir (J and K) India. A total of 100 patients of acquired nasolacrimal duct obstruction were enrolled and divided randomly into two groups, 50 of patients in each group. One group had undergone conventional external DCR operation and other group was treated with DCR surgery with intraoperative mitomycin-C application, in this, 0.2mg/ml MMC was applied at flaps and osteotomy site. Patients were reviewed after 1 week, 1 month, 3 months and 6 months postoperatively. The results of DCR surgeries were evaluated by observation of different parameters such as height of tear of meniscus and patency of the nasolacrimal passage.
doi:10.18410/jebmh/2019/149 fatcat:z7xnwsfgujfzrg6elsg32va6ey