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The locus coeruleus (LC) plays a central role in regulating human cognition, arousal, and autonomic states. Efforts to characterize the LC's function in humans using functional magnetic resonance imaging have been hampered by its small size and location near a large source of noise, the fourth ventricle. We tested whether the ability to characterize LC function is improved by employing neuromelanin-T1 weighted images (nmT1) for LC localization and multi-echo functional magnetic resonancedoi:10.1016/j.neuroimage.2021.118047 pmid:33905860 pmcid:PMC8517932 fatcat:dk4frhoksfft3bngbxeyq5zryq