A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is
Geranylgeranyl transferase regulates CXC chemokine formation in alveolar macrophages and neutrophil recruitment in septic lung injury
American Journal of Physiology - Lung cellular and Molecular Physiology
transferase regulates CXC chemokine formation in alveolar macrophages and neutrophil recruitment in septic lung injury. Overwhelming accumulation of neutrophils is a significant component in septic lung damage, although the signaling mechanisms behind neutrophil infiltration in the lung remain elusive. In the present study, we hypothesized that geranylgeranylation might regulate the inflammatory response in abdominal sepsis. Male C57BL/6 mice received the geranylgeranyl transferase inhibitor,doi:10.1152/ajplung.00199.2012 pmid:23241528 fatcat:tdsrk54tkbcfxhsaite62h5b2e