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To stratify cancer patients for most beneficial therapies, it is a priority to define robust molecular subtypes using clustering methods and big data. If each of these methods produces different numbers of clusters for the same data, it is difficult to achieve an optimal solution. Here, we introduce polyCluster, a tool that reconciles clusters identified by different methods into context-specific subtype communities using a hypergeometric test or a measure of relative proportion of commondoi:10.1101/228551 fatcat:mnrse4fkuzejdox64pqx6ctyfm