Infantile colic has been defined as episodes of excessive and persistent crying without known medical cause. Kangaroo mother care is a new method for case of newborn with several advantages. This study designed for evolution KMC and its effect on infantile colic. Methods: This study is a randomized controlled trial, from 1th may 2008 to 1th may 2009 a total of 70 children, aged 3-12 weeks with persistent colic symptoms that referred to sheikh children hospital (Clinic). Normal mother-infant

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... s were recruited at 3 to 12 weeks of age after obtaining baseline for two days. All cases divided randomly to kangaroo care and conventional care group. For analyzing the data we used 2-sample t test, X² test and fisher exact test. Results: In the begining of study, the kangaroo care group had 3.5hr/d crying and after the intervention, it decreased to 1.7hr/d, the difference were significant (P<0.05). But there were no difference in feeding duration between 2 groups (P=0.2). Awake and content (normal behavior) behaviors were significantly increased in the kangaroo care group (P=0.001). Sleeping duration was significantly increased in the kangaroo care group (P=0.02). Conclusion: Kangaroo care may use as a simple and safe method for colicky infants treatment.