The effects of prenatal cocaine 30mg/kg (s.c.) were analyzed (gestation, day 1-21) and the maternal behavior (biological mother /wet nurse) on the emotional behavior and the voluntary cocaine consumption 30mg/kg, in adult mice. After of the birth each mother raised four biological mice and adopted four (two female and two males, in each group). In 5th week, the prenatal treated mice, the emotional behavior was evaluated, followed by the cocaine intake (30mg/kg) for seven days and again the

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... onal behavior was evaluated. In the second evaluation, the females, were shown more anxious, consuming more water and exploring less. The prenatal cocaine (30 mg/kg) influence more the emotional behavior than the maternal behavior in the average term of the females.