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Rabbit antisera prepared against representative cultures of human cancer cells (SV40 virus-transformed, HeLa, and EB2 cells) showed high cytotoxic specificity for homologous cells when tested against these and cells of other lines and strains. Similar results were observed with antisera against a new cell culture originating from human lung cancer. Antisera against cultures of normal human cells also showed specificity, but relatively low titers. Cross-reactions were observed between HeLa celldoi:10.4049/jimmunol.101.5.1078 fatcat:s2exnsnbvfbkxlhnivzxnijpem