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Brief sensory deprivation triggers cell type-specific structural and functional plasticity in olfactory bulb neurons
Can alterations in experience trigger different plastic modifications in neuronal structure and function, and if so, how do they integrate at the cellular level? To address this question, we interrogated circuitry in the mouse olfactory bulb responsible for the earliest steps in odour processing. We induced experience-dependent plasticity in mice by blocking one nostril for a day, a minimally-invasive manipulation which leaves the sensory organ undamaged and is akin to the natural transientdoi:10.1101/2020.05.10.086926 fatcat:y64wut7nrnardezkgbwyx75sci