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Expanded FLP toolbox for spatiotemporal protein degradation and transcriptomic profiling in C. elegans
[article]
2021
bioRxiv
pre-print
Control of gene expression in specific tissues and/or at certain stages of development allows the study and manipulation of gene function with high precision. Site-specific genome recombination by the Flippase (FLP) and Cre enzymes has proven particularly relevant. Joint efforts of many research groups have led to the creation of efficient FLP and Cre drivers to regulate gene expression in a variety of tissues in Caenorhabditis elegans. Here, we extend this toolkit by the addition of FLP lines
doi:10.1101/2021.12.21.473632
fatcat:h5edjhsrt5bf3ilqpp3lqbcqd4