Immunomodulation of mice blood cells following treatment with free extract of Lactobacillus acidophilus cell

Ebtehal H. Al-Naimy, Ruqaya M. Al-Ezy, Maysaa C. Al-Yas, Muthanna A. S. Al- Mahdawii
2010 Journal of Biotechnology Research Center  
A study aimed to examine immunomodulatory effect of concentrated cell free filtrate (CCF) of Lactobacillus acidophilus on immune system of mice by detecting the total and absolute counts of leucocytes. It was shown that CCF of Lactobacillus acidophilus caused a significant increase in total leucocyte count for all concentrations used in comparison with negative control. However, in absolute leucocyte counts the, CCF of L.acidophilus at doses (500 , 750) mg/kg caused a significant increased in
more » ... mphocyte, neutrophil and monocyte counts, while there was no significant differences in eosinophils and basophil cells number of mice treated with bacterial filtrate. The interaction study showed that the post-treatment with CCF of L. acidophilus caused a significant increase in total leucocytes count and absolute counts of all types of leucocyte cells except basophils and esinophils which showed no significant differences in comparison with pre-treatment
doi:10.24126/jobrc.2010.4.2.134 fatcat:zfq26qf2ubfjxgmdyn64omk63i