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Background. A proinflammatory environment characterized by the continuous activation of the innate immune system is thought to contribute to the markedly elevated mortality in haemodialysis (HD) patients with end-stage renal disease (ESRD). The presence of circulating cell-free DNA (cfDNA) has been demonstrated as biomarker in many pathologies. Methods. We evaluated the occurrence of cfDNA in HD patients and its functional relevance for innate immunity and inflammation. Results. Here, we founddoi:10.1093/ndt/gfr695 pmid:22167588 fatcat:chruq4ntqvfubbzud7sjpieevi