The Characteristics of FDG PET/CT Imaging in Pulmonary Langerhans Cell Sarcoma

Yu-Wen Chen, Chin-Chuan Chang, Po-Nian Hou, Sin-Lin Yin, Yung-Chang Lai, Ming-Feng Hou
2012 Clinical Nuclear Medicine  
A 53-year-old man, who was a heavy smoker, presented with recent severe cough. Radiography demonstrated a large pulmonary mass in the right upper lung. FDG PET/CT demonstrated heterogeneous high-grade activity in the pulmonary mass located in the right upper lung (standardized uptake value of 20), with central necrosis, bilateral upper mediastinal lymphadenopathy, right supraclavicular lymphadenopathy, direct left sternal manubrium invasion, and distal bilateral peripheral lung metastasis.
more » ... logy revealed significant malignant cytologic features and CD1a-and S-100positive cells by immunohistochemistry staining, typical for Langerhans cell sarcoma.
doi:10.1097/rlu.0b013e31824d2256 pmid:22475903 fatcat:2icpen6bmvcuxnhkhvvv3tez3u