Identification of drug repurposing candidates based on a miRNA-mediated drug and pathway network for cardiac hypertrophy and acute myocardial infarction

Jiantao Sun, Jiemei Yang, Jing Chi, Xue Ding, Nan Lv
2018 Human Genomics  
Cardiac hypertrophy and acute myocardial infarction (AMI) are two common heart diseases worldwide. However, research is needed into the exact pathogenesis and effective treatment strategies for these diseases. Recently, microRNAs (miRNAs) have been suggested to regulate the pathological pathways of heart disease, indicating a potential role in novel treatments.
doi:10.1186/s40246-018-0184-0 pmid:30514363 pmcid:PMC6280539 fatcat:uno5r4xrdrf4vcnz6ccjylzeha