A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2017; you can also visit the original URL.
The file type is
The aim of this work is to compare some deterministic optimization algorithms and evolutionary algorithms on parameter estimation in a biological circuit design problem: the negative feedback loop between the tumor suppressor pS3 and the oncogene Mdm2. We compared deterministic optimization algorithms and evolutionary algorithms in terms of robustness of the resulting parameters including all sources of uncertainty into the statistical representation of reference data and evaluating thedoi:10.1109/bibe.2008.4696760 dblp:conf/bibe/NicosiaS08 fatcat:p24am74grjgwnbhcvos4zo6sx4