A study of chemical mediators in patietns with allergic rhinitis. 3. Release of histamine and leukotrienes from in vitro nasal mucosa
アレルギー性鼻炎患者におけるケミカル・メディエーターに関する研究 第三報 in vitroにおける鼻粘膜よりのヒスタミンおよびロイコトリエンの遊離について

TADASHI KOJIMA, KOHJI ASAKURA
1991 Nippon Jibiinkoka Gakkai Kaiho  
Responses to mite antigen and nonimmunological stimuli, substance P, of chopped fragments of nasal mucosae were studied from eleven patients with perennial allergic rhinitis who were sensitive to mite antigen. Amount of released histamine significantly increased by either stimulation. However, the release of leukotrienes (LTs) increased only by the stimulation of mite antigen, which correlated with that of histamine.
doi:10.3950/jibiinkoka.94.587 fatcat:q5kdxmmt5jbrniwxlzlycjbc5q