Glucose, body mass index and pre-neoplastic lesions in the cervix
Glucosa, indice de masa corporal y lesiones preneoplásicas en el cuello uterino

Mónica Navarro-Meza, María Guadalupe Martinez-Rivera, Felipe Santoyo-Telles, María Luisa Pita-López
2011 Ginecología y Obstetricia de México  
The obesity and abnormal blood glucose level has been associated with cervical cancer development; however, few studies have been performed about this relation. Evaluate the blood glucose levels and body mass index (BMI) in women with human papilloma virus infection (HPV-I) and cervical intraepithelial neoplasia (CIN-I). Transversal study of 44 women diagnosed with HPV-I and CIN-I from September to December 2010 in Dysplasia Clinic of Regional Hospital of Guzman City, Federal entity of Jalisco,
more » ... Mexico. The diagnoses were carried by biopsy of cervix, glucose test results were evaluated by spectrophotometry and determinate the BMI. The 18% (n=8) of women were without injury, 41% (n=18), with HPV-I and 41% (n=18) CIN-I. High blood glucose was observed in GIN-I versus without injury in the cervix (p = 0.05), the correlation was OR = 2.6 (95% CI: 1.090-6.52). The young women (19-35 years) were 17% high glucose, 28% normal glucose and 55% low glucose. In group of the medium age (35-65 years) 23% showed high glucose, 50% normal and 27% low. The BMI was not relation with diagnosis, although in the age (young versus age median p=0.001). These results support the proposal about the high levels of glucose in plasma and obesity could be risk cofactors in the development of preneoplasic lesion of cervix.
pmid:22384530 fatcat:fbqkzgfnyjgdvajwbrat3f2gla