ANTICANCER AND ANTIOXIDANT ACTIVITIES OF 2-AMINOBENZOIC ACID (2-OXO-1, 2-DIHYDRO-INDOL-3-YLIDENE) HYDRAZIDES

G Sammaiah, N Narsaiah, J Krishnaveni, G Dayakar, M Sarangapani
2008 Int. J. Chem. Sci   unpublished
In this communication, the anticancer and antioxidant activities of some new 2-aminobenzoic acid (2-oxo-1, 2-dihydro-indol-3-ylidene) hydrazides are presented. The new compounds were prepared by the condensation of indole-2, 3-diones with 2-aminobenzoic acid hydrazide. All the compounds were evaluated for anticancer activity (against HeLa cell lines, IMR-32 cell lines) and antioxidant activity. Some of the compounds exhibited moderate anticancer activity against the cell lines employed and promising antioxidant activity.
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