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De novo mutations drive the spread of macrolide resistant Mycoplasma genitalium : mathematical modelling study
The rapid spread of azithromycin resistance in sexually transmitted infections caused by Mycoplasma genitalium is a growing concern. It is not yet clear to what degree macrolide resistance in M. genitalium results from the emergence of de novo mutations or the transmission of resistant strains. We analysed epidemiological data and developed a compartmental model to investigate the contribution of de novo macrolide resistance mutations to the spread of antimicrobial resistant M. genitalium. Wedoi:10.21256/zhaw-3856 fatcat:bz5iyj7juzdvdatvxmmhud6fu4