Does Exercise Alter Circulating Peripheral Blood Mononuclear Cell Gene Expression In Young Males?

Peter Connolly, Dan Nemet, She-pin Hung, J. Denis Heck, G. Wesley Hatfield, Frank Zaldivar, Vince J. Caiozzo, Dan M. Cooper
2004 Medicine & Science in Sports & Exercise  
Pro-inflammatory cytokines such as interleukin 1 beta (IL-1ß) is known to be increased in obesity and related diseases or metabolic syndrome. To examine the impact of one bout exercise test on circulating IL-1ß levels, twelve sedentarily obese men (45 ± 7) were completed one short time cycling test. Exercise test lasted 15 min with moderate intensity. Blood samples were collected pre and postexercise in order to evaluation serum IL-1ß in all subjects. Statistical analysis was performed with the
more » ... SPSS software version 15.0. P value of <0.05 was accepted as significant. Based on statistical outcome, serum IL-1ß did not change after exercise test when compared with pretest. Our findings indicate that exercise for short time can not affect inflammation profile in sedentary obese individuals. Further studies are needed to clarify possible role of exercise on inflammation in healthy or disease population.
doi:10.1097/00005768-200405001-00413 fatcat:fnwdhritlfh53njwsfqsyaenwm